The purpose of this Notice is to indicate the intent to issue a Request for Applications (RFA), with set-aside funds, to continue the Morris K. Udall Centers of Excellence for Parkinson’s Disease Research program. It is also intended to alert potential applicants, including existing Centers approaching competing renewal, to the change in the Funding Opportunity Announcement (FOA) from Program Announcement (PAR) to RFA. Finally, the Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.