The NINDS is requesting competing renewal applications from Specialized Neuroscience Research Programs (SNRPs) awarded in response to a Request for Applications (RFA) NS-99-001, (http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-99-001.html). This re-competition will continue the unique ongoing research, resource development and education programs of these SNRPs for a one-time renewal cycle.