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ALS and FTD Workshop Agenda


November 12, 2010
Manchester Grand Hyatt Hotel
San Diego, California
Workshop   Participant List   Executive Summary

Agenda

8:30-8:45 a.m.
Welcome from NINDS and The ALS Association
Amelie Gubitz, Ph.D., NINDS, NIH
Lucie Bruijn, Ph.D., The ALS Association
8:45-9:15 a.m.
Current Status of TDP-43 Proteinopathies
Virginia Lee, Ph.D., University of Pennsylvania School of Medicine
9:15-9:45 a.m.
Update on the Search for Gene Defects that Cause Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
Robert Brown, M.D., University of Massachusetts Medical School
9:45-10:15 a.m.
The Molecular Neuropathology of ALS and FTD
Ian Mackenzie, M.D., University of British Columbia
10:15-10:30 a.m.
BREAK
10:30-11:00 a.m.
RNA Targets for TDP-43 and FUS in ALS: Identifying the Basis for Selective Vulnerability
Don Cleveland, Ph.D., Ludwig Institute for Cancer Research
11:00 a.m.-12:30 p.m.

Nonmammalian Models of TDP-43 or FUS/TLS (10-minute presentations each)
Chair: Aaron Gitler, Ph.D., University of Pennsylvania School of Medicine

Speakers:
David Morton, Ph.D., Oregon Health & Science University

Jane Wu, M.D., Ph.D., Northwestern University Feinberg School of Medicine
Randal Tibbetts, Ph.D., University of Wisconsin-Madison
George Jackson, M.D., Ph.D., University of Texas Medical Branch
Fen-Biao Gao, Ph.D., University of Massachusetts Medical School
Christopher Link, Ph.D., University of Colorado, Institute for Behavioral Genetics
Pierre Drapeau, Ph.D., University of Montreal

12:30-1:30 p.m.
Lunch and Poster Viewing
1:30-1:45 p.m.
Introduction: Emerging Rodent Models in ALS and FTD
Lucie Bruijn, Ph.D., The ALS Association
1:45-3:15 p.m.
Rodent Models of TDP-43 or FUS/TLS (10-minute presentations each)
Chair: Jeff Rothstein, M.D., Ph.D., Johns Hopkins University

Speakers:
Jada Lewis, Ph.D., University of Florida
Brian Kraemer, Ph.D., University of Washington
Don Cleveland, Ph.D., Ludwig Institute for Cancer Research
Zuoshang Xu, M.D., Ph.D., University of Massachusetts Medical School
Abraham Acevedo-Arozena, Ph.D., Medical Research Council, Mammalian
Genetics Unit
Robert Baloh, M.D., Ph.D., Washington University
3:15-3:30 p.m.
BREAK
3:30-4:00 p.m.
Making the Most of Mouse Models
Cathleen Lutz, Ph.D., The Jackson Laboratory
4:00-5:00 p.m.

Panel Discussion

  • Future models
  • Resource sharing, compound screening

Best Practice Guidelines for Animal Research in ALS/FTD
Moderator:
Margaret Sutherland, Ph.D., NINDS, NIH

Speakers:
Elizabeth Fisher, Ph.D., University College London
Steve Perrin, Ph.D., ALS Therapy Development Institute
Leonard Petrucelli, Ph.D., Mayo Clinic
J. Paul Taylor, M.D., Ph.D., St. Jude Children’s Research Hospital

5:00-5:15 p.m.
Plans for Moving Forward and Closing Remarks
Amelie Gubitz, Ph.D., NINDS, NIH

Adjourn

Last updated December 23, 2013