Neurodegeneration

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The Neurodegeneration cluster portfolio consists of research on adult onset neurodegenerative diseases of all types, broadly focusing on pathogenesis, treatment and prevention. Research on the normal structure and function of neural systems is also included to enable identification of intervention strategies. The role of the programmatic team is to develop, implement and manage these research programs and to promote the translation of research findings into clinical practice.  Included in the portfolio are topics such as neuronal cell death, protein misfolding, aggregation, and  processing, mitochondrial pathologies, epidemiological studies, genetic studies including GWAS, biomarker studies, clinical studies including deep brain stimulation and gene therapy, and translational projects that will accelerate bench to bedside therapies for neurodegenerative disorders.


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Workshop Summary

Neurodegeneration Funding Initiatives

Neurodegeneration Program Staff


Scientific Staff Research Area
   
Beth-Anne Sieber, Ph.D.
Program Director
Point of contact: PD, ET, HSP, MSA, PSP
Parkinson’s Disease (PD), Essential tremor (ET), Hereditary Spastic Paraplegia (HSA), Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), orphan diseases, molecular biology, neurochemistry, cell biology, Deep Brain Stimulation, gene therapy, motor and non-motor manifestations, clinical trials
   
Margaret Sutherland, Ph.D.
Program Director
Point of contact: HD
Huntington’s Disease (HD), Parkinson’s Disease, GWA studies, genetics, biomarkers, stem cells, protein dynamics, gene silencing, translational research, clinical trials
   
Vacant: Please contact
Margaret Sutherland, Ph.D.
Program Director
Amyotrophic Lateral Sclerosis (ALS), Frontotemporal dementia (FTD)
   
Vacant: Please contact
Beth-Anne Sieber, Ph.D.
Program Director
Alzheimer’s Disease (AD), Vascular Cognitive Impairment (VCI)
   
Ti Lin, Ph.D.
Program Analyst
 
   
Alexander Runko, Ph.D.
Program Analyst



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Address

Neurodegeneration
Neuroscience Center
6001 Executive Blvd.
Rockville, MD 20892