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In the Systems and Cognitive Neuroscience cluster, Dr. Gnadt oversees NINDS funding related to neurophysiological and computational investigation of sensory, sensorimotor and neuroendocrine functions in the brain. Dr. Gnadt came to NINDS in 2008 from a career as a NIH-funded investigator in systems and quantitative neurophysiology since 1986 that spanned appointments at The Salk Institute, University of Alabama at Birmingham (UAB), Stony Brook, Howard and Georgetown Universities. Dr. Gnadt received his PhD in Physiology & Biophysics from UAB in 1985 and was an Alfred P. Sloan Research Fellow from 1993-95. He studied the neurological basis of cognitive, motor and sensory behavior by combining behavioral studies with in vivo & in vitro neurophysiology and systems control analyses. He was also co-developer of an electrophysiological technique for using spectral noise cancellation to allow in situ cancellation of microstimulation artifacts in real-time neural recording.