Clinical Neurocardiology Section - Division of Intramural Research
Skip secondary menu
Groups at NINDS
David S. Goldstein M.D., Ph.D., Senior Investigator
Dr. Goldstein graduated from Yale College and received an M.D.-Ph.D. in Behavioral Sciences from Johns Hopkins. After medical internship and residency at the University of Washington, he came to the NIH as a Clinical Associate in the NHLBI, obtaining tenure as a Senior Investigator in 1984. He joined the NINDS in 1990 to head the Clinical Neurochemistry Section and founded and directs the Clinical Neurocardiology Section, an independent Section. He has received Yale's Angier Prize for Research in Psychology, the Laufberger Medal of the Czech Academy of Sciences, 2 NIH Merit Awards, the Founders Award of the Bakken Heart-Brain Institute, and the NIH Distinguished Clinical Teacher Award. He is author of more than 450 research articles and several books, including "Adrenaline and the Inner World: An Introduction to Scientific Integrative Medicine," the "NDRF Handbook for Patients with Dysautonomias," "Stress, Catecholamines, and Cardiovascular Disease," and "The Autonomic Nervous System in Health and Disease.
Laboratory Staff
Nelson Cole, Ph.D. Contractor 301-435- 8721
Courtney Holmes, C.M.T. Biologist 301-496- 7832
Tereza Jenkins, Secretary/Patient Care Coordinator 301-496- 1115
Irwin Kopin, M.D. Scientist Emeritus 301-496- 4297
Neptune Mizrahi, Ph.D., M.P.H Post-Doctoral IRTA 301-402- 9442
Sandra Pechnik, R.N. Research Nurse 301-435- 5166
LaToya Sewell, Nurse Practitioner 301-451- 1670
Yehonatan Sharabi, M.D. Adjunct Clinical Investigator 301-402- 2052
Research Interests
Dr. Goldstein's main research interests are in clinical neurocardiology, catecholamine systems, and scientific integrative medicine. The Clinical Neurocardiology Section carries out mainly patient-oriented research about disorders of brain regulation of the cardiovascular system. The research emphasizes diseases of the autonomic nervous system, where the sympathetic nervous system or catecholamines play important roles, such as autonomic failure syndrome and neurogenetic conditions featuring abnormal catecholamine synthesis or metabolism. The Section operates a renowned Clinical Neurochemistry Laboratory for assays of levels of catecholamines and their metabolites. Current research of the Section focuses on biomarkers and mechanisms of Parkinson disease and related disorders that involve abnormal catecholamine systems. Selected Recent PublicationsGoldstein DS.
Adrenaline and the Inner World: An Introduction to Scientific Integrative Medicine - Johns Hopkins University Press 2006 Goldstein DS, Eisenhofer G, Kopin IJ.
Sources and significance of plasma levels of catechols and their metabolites in humans - J Pharmacol Exp Ther 305 800-811 2003 Goldstein DS, Smith LJ
The NDRF Handbook for Patients with Dysautonomias - Futura 2002 Goldstein DS
The Autonomic Nervous System in Health and Disease - Taylor & Francis 2001 Goldstein DS, Holmes C, Cannon RO III, Eisenhofer G, Kopin IJ
Sympathetic cardioneuropathy in dysautonomias - N Engl J Med 336 696-702 1997 Goldstein DS
Stress, Catecholamines, and Cardiovascular Disease - Oxford Univ. Press 1995
Contact Information
Clinical Neurocardiology Section, CNP, DIR, NINDS, NIH Building 10, Room 6N252 10 Center Drive, MSC 1620 Bethesda MD 20892-1620
Telephone: 301-496- 2103 (office), 301- 496-7832 (laboratory), 301-402- 0180 (fax), Email: goldsteind@ninds.nih.gov
At NINDS
NINDS Staff
Advisory Council
| Labs at NINDS |
Government
Other NIH Institutes
Government Resources
Other related groups
Organizations
Professional Societies
NINDS is part of the
National Institutes of
Health
David S. Goldstein M.D., Ph.D., Senior Investigator
Dr. Goldstein graduated from Yale College and received an M.D.-Ph.D. in Behavioral Sciences from Johns Hopkins. After medical internship and residency at the University of Washington, he came to the NIH as a Clinical Associate in the NHLBI, obtaining tenure as a Senior Investigator in 1984. He joined the NINDS in 1990 to head the Clinical Neurochemistry Section and founded and directs the Clinical Neurocardiology Section, an independent Section. He has received Yale's Angier Prize for Research in Psychology, the Laufberger Medal of the Czech Academy of Sciences, 2 NIH Merit Awards, the Founders Award of the Bakken Heart-Brain Institute, and the NIH Distinguished Clinical Teacher Award. He is author of more than 450 research articles and several books, including "Adrenaline and the Inner World: An Introduction to Scientific Integrative Medicine," the "NDRF Handbook for Patients with Dysautonomias," "Stress, Catecholamines, and Cardiovascular Disease," and "The Autonomic Nervous System in Health and Disease.
Laboratory Staff
Nelson Cole, Ph.D. Contractor 301-435- 8721
Courtney Holmes, C.M.T. Biologist 301-496- 7832
Tereza Jenkins, Secretary/Patient Care Coordinator 301-496- 1115
Irwin Kopin, M.D. Scientist Emeritus 301-496- 4297
Neptune Mizrahi, Ph.D., M.P.H Post-Doctoral IRTA 301-402- 9442
Sandra Pechnik, R.N. Research Nurse 301-435- 5166
LaToya Sewell, Nurse Practitioner 301-451- 1670
Yehonatan Sharabi, M.D. Adjunct Clinical Investigator 301-402- 2052
Research Interests
Dr. Goldstein's main research interests are in clinical neurocardiology, catecholamine systems, and scientific integrative medicine. The Clinical Neurocardiology Section carries out mainly patient-oriented research about disorders of brain regulation of the cardiovascular system. The research emphasizes diseases of the autonomic nervous system, where the sympathetic nervous system or catecholamines play important roles, such as autonomic failure syndrome and neurogenetic conditions featuring abnormal catecholamine synthesis or metabolism. The Section operates a renowned Clinical Neurochemistry Laboratory for assays of levels of catecholamines and their metabolites. Current research of the Section focuses on biomarkers and mechanisms of Parkinson disease and related disorders that involve abnormal catecholamine systems. Selected Recent PublicationsGoldstein DS.
Adrenaline and the Inner World: An Introduction to Scientific Integrative Medicine - Johns Hopkins University Press 2006 Goldstein DS, Eisenhofer G, Kopin IJ.
Sources and significance of plasma levels of catechols and their metabolites in humans - J Pharmacol Exp Ther 305 800-811 2003 Goldstein DS, Smith LJ
The NDRF Handbook for Patients with Dysautonomias - Futura 2002 Goldstein DS
The Autonomic Nervous System in Health and Disease - Taylor & Francis 2001 Goldstein DS, Holmes C, Cannon RO III, Eisenhofer G, Kopin IJ
Sympathetic cardioneuropathy in dysautonomias - N Engl J Med 336 696-702 1997 Goldstein DS
Stress, Catecholamines, and Cardiovascular Disease - Oxford Univ. Press 1995
Contact Information
Clinical Neurocardiology Section, CNP, DIR, NINDS, NIH Building 10, Room 6N252 10 Center Drive, MSC 1620 Bethesda MD 20892-1620
Telephone: 301-496- 2103 (office), 301- 496-7832 (laboratory), 301-402- 0180 (fax), Email: goldsteind@ninds.nih.gov