Advanced MRI Section - Division of Intramural Research
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Jeff H. Duyn Ph.D., Investigator
Dr. Duyn received his M.Sc. and Ph.D. degrees in physics at the University of Delft, Holland where he was involved with the development of X-ray diffraction techniques, as well as the early development of magnetic resonance imaging (MRI). During his postdoctoral assignments at the University of California, San Francisco, and at NIH, his research focused on the study of human brain physiology, as measured by spectroscopic and functional MRI techniques. Dr. Duyn moved to NINDS in 2000.
Laboratory Staff
Jacco de Zwart, Ph.D. Staff Scientist 301-594- 7315
Masaki Fukunaga, Ph.D. Visiting Fellow 301-594- 7312
Susan Fulton, Medical Technologist 301-451- 9912
Silvina Horovitz, Ph.D. Research Fellow
J Jansma, Ph.D. Postdoctoral Fellow 301-451- 9919
Lei Qin, Special Volunteer 301-451- 9917
Karin Shmueli, Ph.D. Visiting Fellow 301-451- 9916
Peter van Gelderen, Ph.D. Staff Scientist 301-402- 1472
Research Interests
In addition to providing structural information, MRI has the potential to non-invasively map physiologic parameters and function. The current research focus is to optimally exploit this potential by investigating the mechanisms behind MRI contrast, exploring avenues to manipulate the contrast, and optimizing MRI data acquisition and analysis to achieve optimum sensitivity, resolution, reliability, and accuracy. Specific aims are the development of MRI techniques for the measurements of structural anatomy, tissue metabolism, tissue perfusion, and blood oxygenation level dependent contrast in both normal and diseased human brain. Selected Recent PublicationsF.J. Langheim, J.H. Callicott, V.S. Mattay, J.H. Duyn, D.R. Weinberger
Cortical Systems Associated with Covert Music Rehearsal - NeuroImage 16 (4) 901-8 2002 M.N. Yongbi, F. Fera, J.A. Frank, V.S. Mattay, J.H. Duyn
Comparison of Multi-Slice Baseline and fMRI Perfusion Signal at 1.5T and 3.0T Using Pulsed Arterial Spin Labeling: Initial Results in Six Subjects - Radiology 222 569-575 2002 E.L. Barbier, S. Marrett, A. Danek, A. Vortmeyer, P. van Gelderen, J. Duyn, P. Bandettini, J. Grafman, A.P. Koretsky
Imaging Cortical Anatomy by High Resolution MR at 3.0T: Detection of the Stripe of Gennari in Visual Area 17 - Magn. Resonance Med. 48 (4) 738-8 2002 G. Tedeschi, S. Bonavita, H.F. McFarland, N. Richert, J.H. Duyn, J.A. Frank
Proton MR Spectroscopic Imaging in Multiple Schlerosis - Neuroradiology 44 (1) 37-42 2002 J.A. de Zwart, P. van Gelderen, P. Kellman, J.H. Duyn
Application of Sensitivity-Encoded Echo-Planar Imaging for Blood Oxygen Level-Dependent Functional Brain Imaging - Magn. Resonance Med. 48 (6) 1011-20 2002 J.A. de Zwart, P. van Gelderen, P. Kellman, J.H. Duyn
Reduction of Gradient Acoustic Noise in MRI Using SENSE-EPI - NeuroImage 16 (4) 1151-5 2002
Contact Information
Advanced MRI Section Laboratory of Functional and Molecular Imaging, NINDS Building 10, Room B1D724 10 Center Drive, MSC 1065 Bethesda MD 20892-1065
Telephone: 301-594- 7305 (office), 301- 594-7305 (laboratory), 301-594- 7315 (fax), Email: jhd@helix.nih.gov
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Jeff H. Duyn Ph.D., Investigator
Dr. Duyn received his M.Sc. and Ph.D. degrees in physics at the University of Delft, Holland where he was involved with the development of X-ray diffraction techniques, as well as the early development of magnetic resonance imaging (MRI). During his postdoctoral assignments at the University of California, San Francisco, and at NIH, his research focused on the study of human brain physiology, as measured by spectroscopic and functional MRI techniques. Dr. Duyn moved to NINDS in 2000.
Laboratory Staff
Jacco de Zwart, Ph.D. Staff Scientist 301-594- 7315
Masaki Fukunaga, Ph.D. Visiting Fellow 301-594- 7312
Susan Fulton, Medical Technologist 301-451- 9912
Silvina Horovitz, Ph.D. Research Fellow
J Jansma, Ph.D. Postdoctoral Fellow 301-451- 9919
Lei Qin, Special Volunteer 301-451- 9917
Karin Shmueli, Ph.D. Visiting Fellow 301-451- 9916
Peter van Gelderen, Ph.D. Staff Scientist 301-402- 1472
Research Interests
In addition to providing structural information, MRI has the potential to non-invasively map physiologic parameters and function. The current research focus is to optimally exploit this potential by investigating the mechanisms behind MRI contrast, exploring avenues to manipulate the contrast, and optimizing MRI data acquisition and analysis to achieve optimum sensitivity, resolution, reliability, and accuracy. Specific aims are the development of MRI techniques for the measurements of structural anatomy, tissue metabolism, tissue perfusion, and blood oxygenation level dependent contrast in both normal and diseased human brain. Selected Recent PublicationsF.J. Langheim, J.H. Callicott, V.S. Mattay, J.H. Duyn, D.R. Weinberger
Cortical Systems Associated with Covert Music Rehearsal - NeuroImage 16 (4) 901-8 2002 M.N. Yongbi, F. Fera, J.A. Frank, V.S. Mattay, J.H. Duyn
Comparison of Multi-Slice Baseline and fMRI Perfusion Signal at 1.5T and 3.0T Using Pulsed Arterial Spin Labeling: Initial Results in Six Subjects - Radiology 222 569-575 2002 E.L. Barbier, S. Marrett, A. Danek, A. Vortmeyer, P. van Gelderen, J. Duyn, P. Bandettini, J. Grafman, A.P. Koretsky
Imaging Cortical Anatomy by High Resolution MR at 3.0T: Detection of the Stripe of Gennari in Visual Area 17 - Magn. Resonance Med. 48 (4) 738-8 2002 G. Tedeschi, S. Bonavita, H.F. McFarland, N. Richert, J.H. Duyn, J.A. Frank
Proton MR Spectroscopic Imaging in Multiple Schlerosis - Neuroradiology 44 (1) 37-42 2002 J.A. de Zwart, P. van Gelderen, P. Kellman, J.H. Duyn
Application of Sensitivity-Encoded Echo-Planar Imaging for Blood Oxygen Level-Dependent Functional Brain Imaging - Magn. Resonance Med. 48 (6) 1011-20 2002 J.A. de Zwart, P. van Gelderen, P. Kellman, J.H. Duyn
Reduction of Gradient Acoustic Noise in MRI Using SENSE-EPI - NeuroImage 16 (4) 1151-5 2002
Contact Information
Advanced MRI Section Laboratory of Functional and Molecular Imaging, NINDS Building 10, Room B1D724 10 Center Drive, MSC 1065 Bethesda MD 20892-1065
Telephone: 301-594- 7305 (office), 301- 594-7305 (laboratory), 301-594- 7315 (fax), Email: jhd@helix.nih.gov