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Transient Ischemic Attack Press Releases

Illustration of ischemic stroke

Diabetes drug may prevent recurring strokes
Wednesday, Feb 17, 2016
Pioglitazone, a drug used for type 2 diabetes, may prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes. The results of the Insulin Resistance Intervention after Stroke (IRIS) trial, presented at the International Stroke Conference 2016 in Los Angeles and published in the New England Journal of Medicine, suggest a potential new method to prevent stroke and heart attack in high-risk patients who have already had one stroke or transient ischemic attack.

New NIH logo

NIH-funded study suggests that moving more may lower stroke risk
Thursday, Jul 18, 2013
Here’s yet another reason to get off the couch: new research findings suggest that regularly breaking a sweat may lower the risk of having a stroke. A stroke can occur when a blood vessel in the brain gets blocked. As a result, nearby brain cells will die after not getting enough oxygen and other nutrients. A number of risk factors for stroke have been identified, including smoking, high blood pressure, diabetes and being inactive.


Aspirin-clopidogrel no better than aspirin alone for patients with lacunar stroke
Wednesday, Aug 29, 2012
An NIH-funded trial has found that aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, which are typically small strokes that occur deep within the brain. The trial also found that whether patients received aspirin or the dual therapy, their stroke risk was reduced more than three-fold from what it was 10 years ago.

The brain and its major arteries

NIH stroke prevention trial has immediate implications for clinical practice
Wednesday, Sep 7, 2011
Patients at a high risk for a second stroke who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to the medical treatment, a large nationwide clinical trial has shown. New enrollment in the study was stopped in April because early data showed significantly more strokes and deaths occurred among the stented patients at the 30-day mark.

An illustration of the carotid arteries running through a man's neck.

Landmark NIH Clinical Trial Comparing Two Stroke Prevention Procedures Shows Surgery and Stenting Equally Safe and Effective
Wednesday, May 26, 2010
A major study of people at risk for stroke showed that two medical procedures designed to prevent strokes are safe and effective overall. In the trial of 2,502 participants, carotid endarterectomy, a gold-standard surgical procedure, was compared to carotid artery stenting, a newer and less invasive procedure.

Is It Just a Headache? Study Links Migraine to Brain Damage in Mice
Friday, Nov 16, 2007
Migraine headaches are a source of disabling pain for millions of people.  Now, a study in mice suggests that these headaches may be linked to tiny areas of stroke-like brain damage.  The findings suggest that treatment to prevent migraines may also prevent longer-term cognitive problems.

Developing Tools to Detect Cognitive Impairment from Silent Strokes
Monday, Nov 6, 2006
Scientists from the National Institute of Neurological Disorders and Stroke (NINDS) and the Canadian Stroke Network recently wrapped up a workshop – the first of its kind – aimed at harmonizing clinical and research tools for assessing vascular cognitive impairment (VCI), a common disability linked to stroke.

Aspirin is Safer than Warfarin and Just as Effective for Treating Blocked Arteries in the Brain
Wednesday, Mar 30, 2005
To reduce the risk of stroke, partial blockage of arteries in the brain (intracranial stenosis) has for decades been treated with drugs such as aspirin and warfarin that reduce blood clotting. However, doctors have never had good evidence for choosing one therapy over the other. Now, results of a double-blind, randomized clinical trial show for the first time that aspirin works as well as warfarin with fewer side effects.

Preconditioning the brain may protect against stroke
Tuesday, Jan 13, 2004
A December 2003 news article on genetic changes to protect the brain against a second larger stroke, prepared by the National Institute of Neurological Disorders and Stroke (NINDS).
Fact Sheet

Estrogen Doesn't Prevent Second Strokes: Protective Effects of Hormone Replacement Therapy Challenged
Thursday, Oct 25, 2001
Estrogen hormone replacement therapy does not reduce the risk of stroke or death in postmenopausal women who have already had a stroke or a transient ischemic attack (TIA), according to a report from the first randomized, controlled clinical trial of estrogen therapy for secondary prevention of cerebrovascular disease.
Fact Sheet

Benefits of Surgery for Some Patients at High Risk for Stroke
Tuesday, Feb 26, 1991
Overwhelming evidence from an ongoing clinical trial shows that the surgical removal of fatty deposits from the the main artery in the neck supplying blood to the brain is highly effective in reducing strokes for patients who have a severely narrowed carotid artery and have previously had a stroke or symptoms of a stroke.