Narcolepsy Press ReleasesGenetic Study Confirms the Immune System’s Role in Narcolepsy
Sunday, May 3, 2009
Scientists funded by the National Institutes of Health have identified a gene associated with narcolepsy, a disorder that
causes disabling daytime sleepiness, sleep attacks, irresistible bouts of sleep that can strike at any time, and disturbed
sleep at night. The gene has a known role in the immune system, which strongly suggests that autoimmunity, in which the immune
system turns against the body's own tissues, plays an important role in the disorder.Study in Dogs Shows that Histamine is Key to Wakefulness
Thursday, Sep 23, 2004
Scientists Pinpoint Possible Cause for Debilitating Sleep Disorder Narcolepsy
Scientists studying an animal model of narcolepsy have found that histamine-activated brain cells are key to wakefulness.
The findings help to show why antihistamines, commonly used to treat colds and allergies, cause drowsiness and impair alertness.
Tuesday, Aug 29, 2000
Stanford Researchers Nab Gene For Sleep Disorder
Scientists believe they may have identified the cause of the debilitating sleep disorder narcolepsy in humans. A new study
shows a dramatic reduction — up to 95 percent — in the number of neurons containing a substance called hypocretins in the
brains of people with narcolepsy compared to control brains. Hypocretin peptides are neurotransmitters that play an important
role in regulating sleep and appetite. The researchers hypothesize that the pronounced loss of these neurons could be caused
either by a neurodegenerative process or an autoimmune response. Fact Sheet
Thursday, Aug 5, 1999
After a decade-long search, a Stanford-led team has identified a gene that causes the sleep disorder narcolepsy -- a breakthrough
that brings a cure for this disabling condition within reach, the scientists say.