NINDS Multiple System Atrophy Information Page

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Condensed from Multiple System Atrophy Fact Sheet

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What is Multiple System Atrophy?

Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by symptoms of autonomic nervous system failure such as fainting spells and bladder control problems, combined with motor control symptoms such as tremor, rigidity, and loss of muscle coordination. MSA affects both men and women primarily in their 50s.

Is there any treatment?

There is no cure for MSA. Currently, there are no treatments to delay the progress of neurodegeneration in the brain. But there are treatments available to help people cope with some of the more disabling symptoms of MSA.

What is the prognosis?

The disease tends to advance rapidly over the course of 9 to 10 years, with progressive loss of motor skills, eventual confinement to bed, and death. There is no remission from the disease. There is currently no cure.

What research is being done?

The NINDS supports research about MSA through grants to major medical institutions across the country. In 2007, the NINDS sponsored a consensus conference that brought together experts from around the world to review and update the diagnostic criteria for MSA. These new diagnostic guidelines are helping doctors make quicker and more accurate diagnoses of MSA. A great deal of research is ongoing to learn why synuclein buildup occurs in MSA and Parkinson’s disease, and how to prevent it.

NIH Patient Recruitment for Multiple System Atrophy Clinical Trials

Organizations

Dysautonomia Foundation
315 W. 39th Street
Suite 701
New York, NY   10018
info@familialdysautonomia.org
http://www.familialdysautonomia.org
Tel: 212-279-1066
Fax: 212-279-2066

Familial Dysautonomia Hope Foundation, Inc. (FD Hope)
121 South Estes Drive
Suite 205-D
Chapel Hill, NC   27514-2868
info@fdhope.org
http://www.fdhope.org
Tel: 919-969-6636

National Dysautonomia Research Foundation
P.O. Box 301
Red Wing, MN   55066-0301
ndrf@ndrf.org
http://www.ndrf.org
Tel: 651-267-0525
Fax: 651-267-0524

Shy-Drager/Multiple System Atrophy Support Group, Inc.
P.O. Box 279
Coupland, TX   78615
http://www.shy-drager.org
Tel: 866-SDS-4999 (737-4999)
Fax: 512-251-3315



Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892



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Last updated July 02, 2009