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Coma Press Releases

Cellular energy factories

PINK1 protein crucial for removing broken-down energy reactors
Wednesday, Aug 12, 2015
Cells are powered by tiny energy reactors called mitochondria. When damaged, they leak destructive molecules that can cause substantial harm and eventually kill brain cells. Scientists at the NIH’s National Institute of Neurological Disorders and Stroke (NINDS) showed that a protein called PINK1 that is implicated in Parkinson’s disease is critical for helping cells get rid of dysfunctional mitochondria.

A DTI scan shows the many nerve fiber tracts that run through a healthy brain (viewed face-on).  The tracts look like mutlti-colored threads that fill in the outline of a brain.

Diffusion Tensor Imaging May Improve Diagnosis and Tracking of Mild Traumatic Brain Injuries
Thursday, Mar 4, 2010
Investigators have found that a state-of-the-art brain imaging method may be useful for detecting and monitoring mild traumatic brain injury, a controversial diagnosis that is based largely on a patient’s subjective experience. A mild traumatic brain injury typically involves no sign of damage based on a neurological exam or standard brain imaging techniques.

Thumbnail Brain Sleep

The Sleeping Brain Yields Clues to the Conscious Mind
Monday, Jul 27, 2009
Recent studies have used brain imaging to identify the parts of our brains that underlie emotions from love to disgust, and behaviors from solving math problems to solving moral problems. Now, NIH scientists are probing the very basis of conscious thought by examining differences in brain activity between wakefulness and sleep.

New Technique Removes Toxic Protein and Prevents Memory Impairment in Alzheimer's Disease Model
Wednesday, Dec 5, 2007
Increasing the activity of a key protein in the bloodstream slows the buildup of a toxic substance in the brains of mice with the gene mutation for Alzheimer's disease (AD). It also prevents some memory problems, a new study shows. If the approach works in humans, it may eventually lead to a way of preventing or halting AD.

Evaluation of Patients Treated With Natalizumab Finds No New Cases of Progressive Multifocal Leukoencephalopathy
Wednesday, Mar 1, 2006
An independent clinical and laboratory study of more than 3000 people treated with the drug natalizumab (Tysabri®) for multiple sclerosis (MS), Crohn’s disease, and rheumatoid arthritis has found no evidence of new cases of the often-fatal disorder called progressive multifocal leukoencephalopathy (PML). The laboratory component of the study was coordinated by the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH), working in conjunction with the NIH Clinical Center.

Study Links Restless Legs Syndrome to Poor Iron Uptake in the Brain
Monday, Aug 11, 2003
Results of the first-ever autopsy study of brains from people with restless legs syndrome (RLS) suggest that the disorder may result from inefficient processing of iron in certain brain cells. The findings provide a possible explanation for this disorder and may lead to new ways of treating the disease.
Fact Sheet

Pressure Combined with Heat Reduces Prion Infectivity in Processed Meats
Monday, May 5, 2003
The combination of high temperature and very high pressure in the preparation of processed meats such as hot dogs and salami may effectively reduce the presence of infective prions while retaining the taste, texture, and look of these meats, according to a new study.
Fact Sheet

NIH Scientists Identify Gene for Fatal Childhood Disorder, Niemann-Pick Type C: Finding Points to Critical New Steps in Cholesterol Processing
Thursday, Jul 10, 1997
Bethesda, MD -- After decades of work, scientists at the National Institutes of Health have identified a gene alteration associated with the fatal childhood cholesterol disorder Niemann-Pick type C (NPC). Learning how the gene functions may lead to the first effective treatment for the disease and to a fundamental new understanding of how cholesterol is processed in the body.