The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, is looking for individuals to participate in clinical studies. Participating in clinical trials allows you to play an active role in research on the nature and causes of many disorders of the brain and nervous system, and to possibly help physician-scientists develop future treatments. The information below is designed to help you quickly learn about actively recruiting research studies for which you or someone you know may be eligible.
The purpose of this study is to discover early signs of autism in children with tuberous sclerosis complex (TSC)—a population in which autism is common. This 5-year, multi-site study will use various tests—including magnetic resonance imaging (MRI) and electroencephalogram (EEG)—to identify developmental precursors of autism spectrum disorders in children with TSC.
A total of 150 infants will be enrolled at 5 TSC centers throughout the United States. The main goal is to pinpoint early signs of autism by studying the brain using MRI, EEG, and behavioral/neuropsychological tests. Eligible infants between the ages of 3-12 months will be evaluated at regular intervals over time until they reach 3 years of age. Throughout the study, investigators will recommend intervention services for any child who shows signs of autism.
*Enrollment of subjects <36 weeks gestation may be considered on a case by case basis depending on presence and extent of prenatal and/or perinatal complications.
Last Reviewed February 2, 2016