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Cerebral Palsy Press Releases


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Closing in on risk factors for cerebral palsy and infant death
Monday, Sep 9, 2013
Karin B. Nelson, M.D., scientist emeritus at the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, and her colleagues from the University of Sydney, the University of Western Australia and Sydney Adventist Hospital in Australia examined the degree to which four specific risk factors contributed to cerebral palsy and young infant death.

Neurons in this brain section from a newborn mouse appear as different colors depending on whether they have low (blue) or high (red) levels of chloride, which is a sign that the neurons are still maturing.  From Neuron, Sept. 2009, Vol. 63, pp. 1-16.

Better Understanding of Newborn Seizures Leads to Potential New Treatment
Thursday, Oct 29, 2009
Commonly used anti-seizure medications do not work as effectively in newborns as they do in adults and children.  A new study funded by the National Institute of Neurological Disorders and Stroke (NINDS) helps explain why, and suggests that effective treatment for newborn seizures could be a matter of repurposing an available drug and using it to supplement conventional anti-seizure therapies.

Common Treatment to Delay Labor Decreases Preterm Infants' Risk for Cerebral Palsy
Thursday, Aug 28, 2008
Preterm infants born to mothers receiving intravenous magnesium sulfate — a common treatment to delay labor — are less likely to develop cerebral palsy than are preterm infants whose mothers do not receive it, report researchers in a large National Institutes of Health research network.

Arthritis Drug Shows Promise for Reducing Brain Hemorrhage in Premature Babies
Monday, Aug 27, 2007
A drug that is commonly used to reduce the pain of arthritis may eventually be used in pregnant women with preterm labor to lessen the risk of brain damage in very low birthweight babies, a new study suggests.

New Neurons are Born: Animal Model of Premature Babies Shows Evidence of Neuronal Recovery After Brain Injury
Wednesday, Jul 12, 2006
Research funded in part by the National Institute of Neurological Disorders and Stroke (NINDS) shows that mice with a brain injury similar to that of many premature babies can generate new neurons that help to repair the damage. The study is the first to show that substantial recovery from neonatal injury can occur in the developing brain. The finding helps to explain why many children born prematurely with very low birth weight are able to overcome their early difficulties.

New Device Detects Fetal Brain Response to Light: May Help Prevent Brain Damage
Thursday, Sep 5, 2002
For years, doctors who work in maternal and fetal medicine have had no way to detect brain activity in unborn children. Now, for the first time, researchers using a unique scanning device have shown that they can detect fetal brain activity in response to flashes of light transmitted through the mother's abdomen. With refinement, this technique may help physicians detect and prevent fetal brain damage resulting from maternal hypertension, diabetes, and other conditions.

Blood Markers Associated with Autism and Mental Retardation
Wednesday, Apr 25, 2001
A new study shows that elevated concentrations of proteins present at birth in the blood may be associated with the development of autism and mental retardation later in childhood. The identification of a biological marker early in life and before the onset of symptoms could lead to earlier and more definitive diagnoses, better clinical definitions, and the discovery of interventional therapies for the disorders.
Fact Sheet

Transplanted Neural Stem Cells Migrate Throughout the Abnormal Brain, Reduce Disease Symptoms
Monday, Jun 7, 1999
For years, researchers have probed the mysteries of neural stem cells -- immature cells that can differentiate into all the cell types that make up the brain -- with the idea that they might be useful for treating brain disorders such as Parkinson's disease. Important new animal research now suggests that these cells may be effective in treating a much broader array of brain diseases than previously anticipated, including Alzheimer's disease and many childhood brain disorders.

Study Ties Cerebral Palsy to Inflammation and Blood-Clotting Abnormalities
Thursday, Oct 1, 1998
Groundbreaking new research provides strong evidence that inflammation and clotting abnormalities may be important causes of cerebral palsy (CP) in full-term babies, who account for about half of all children with this disorder. The study may lead to ways of identifying babies at risk for CP and ultimately to new therapies that might prevent brain damage in some children.

Study Links Neonatal Thyroid Function to Cerebral Palsy
Wednesday, Mar 27, 1996
Scientists have linked low levels of a thyroid hormone in premature infants to the development of disabling cerebral palsy. They examined more than 400 premature infants screened for blood levels of the hormone thyroxine during the first week of life. They found that infants with low levels of thyroxine at birth had a 3- to 4-fold increase in the incidence of disabling cerebral palsy at age 2.

Common Drug Linked to Lower Incidence of Cerebral Palsy
Wednesday, Feb 8, 1995
A new study shows that very low birthweight babies have a lower incidence of cerebral palsy (CP) when their mothers are treated with magnesium sulfate soon before giving birth. The findings come from a study sponsored by the California Birth Defects Monitoring Program (CBDMP) and the National Institute of Neurological Disorders and Stroke (NINDS) and reported in the February 1995 issue of Pediatrics.

Treatment reduces brain hemorrhages in very low birthweight babies
Monday, Apr 11, 1994
Very low-birthweight babies who are treated with indomethacin within 6-12 hours after birth have a lower incidence and reduced severity of brain hemorrhage, a frequent and often debilitating complication of such births. This conclusion is being published in the April 1994 issue of Pediatrics,* based on the results of a large multicenter clinical trial sponsored by the National Institute of Neurological Disorders and Stroke (NINDS).

Study Links Twin Births to Cerebral Palsy
Wednesday, Dec 8, 1993
The current rise in multiple births may contribute to an increase in children born with cerebral palsy (CP), according to a report published in the December issue of Pediatrics. In a study involving more than 155,000 children, researchers from the National Institute of Neurological Disorders and Stroke (NINDS) and the California Birth Defects Monitoring Program (CBDMP) found that twin pregnancies produced a child with CP more than 10 times as often as pregnancies producing a single child.