The brachial plexus is a network of nerves that conducts signals from the spine to the shoulder, arm, and hand. Brachial plexus injuries are caused by damage to those nerves. Symptoms may include a limp or paralyzed arm; lack of muscle control in the arm, hand, or wrist; and a lack of feeling or sensation in the arm or hand.   Brachial plexus injuries can occur as a result of shoulder trauma, tumors, or inflammation.  There is a rare syndrome called Parsonage-Turner Syndrome, or brachial plexitis, which causes inflammation of the brachial plexus without any obvious shoulder injury.  This syndrome can begin with severe shoulder or arm pain followed by weakness and numbness. In infants, brachial plexus injuries may happen during birth if the baby’s shoulder is stretched during passage in the birth canal (see Brachial Plexus Birth Injuries).   The severity of a brachial plexus injury is determined by the type of damage done to the nerves.  The most severe type, avulsion, is caused when the nerve root is severed or cut from the spinal cord.  There is also an incomplete form of avulsion in which part of the nerve is damaged and which leaves some opportunity for the nerve to slowly recover function.   Neuropraxia, or stretch injury, is the mildest type of injury   Neuropraxia damages the protective covering of the nerve, which causes problems with nerve signal conduction, but does not always damage the nerve underneath. Some brachial plexus injuries may heal without treatment. Many children who are injured during birth improve or recover by 3 to 4 months of age. Treatment for brachial plexus injuries includes physical therapy and, in some cases, surgery. The site and type of brachial plexus injury determines the prognosis. For avulsion and rupture injuries, there is no potential for recovery unless surgical reconnection is made in a timely manner. The potential for recovery varies for neuroma and neuropraxia injuries. Most individuals with neuropraxia injuries recover spontaneously with a 90-100% return of function. The NINDS conducts and supports research on injuries to the nervous system such as brachial plexus injuries. Much of this research is aimed at finding ways to prevent and treat these disorders. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&term=(brachial+plexus/injuries[majr])+OR+(brachial+plexus[MAJR]+AND+Wounds+AND+Injuries[MESH])+AND+human[mh]+AND+english[la]+AND+(review[ptyp]+OR+review+literature[mh]+OR+practice+guideline[ptyp]+OR+guideline[ptyp]+OR+clinical+trials[mh]+OR+clinical+trial[ptyp]+OR+consumerj[sb])&db=PubMed&orig_db=PubMed&filters=on&pmfilter_EDatLimit=5+Years 2 http://clinicaltrials.gov/ct2/results?term= /disorders/brachial_plexus/pubs_brachial_plexus.htm /disorders/brachial_plexus/xml_brachial_plexus.xml xml_brachial_plexus.xml Erb's Palsy V123 National Rehabilitation Information Center (NARIC)

8201 Corporate Drive

Suite 600 Landover MD 20785 naricinfo@heitechservices.com http://www.naric.com 301-459-5900/301-459-5984 (TTY) 800-346-2742 301-562-2401 V91 National Organization for Rare Disorders (NORD)

55 Kenosia Avenue

Danbury CT 06810 orphan@rarediseases.org http://www.rarediseases.org 203-744-0100 Voice Mail 800-999-NORD (6673) 203-798-2291 Federation of voluntary health organizations dedicated to helping people with rare "orphan" diseases and assisting the organizations that serve them. Committed to the identification, treatment, and cure of rare disorders through programs of education, advocacy, research, and service. V310 United Brachial Plexus Network

1610 Kent Street

Kent OH 44240 info@ubpn.org http://www.ubpn.org 866-877-7004 866-877-7004 Non-profit organization devoted to providing information, support and leadership for families and those concerned with brachial plexus injuries and their prevention worldwide. V583 National Institute on Disability and Rehabilitation Research (NIDRR)

U.S. Department of Education Office of Special Education and Rehabilitative Services

400 Maryland Ave., S.W. Washington DC 20202-7100 http://www.ed.gov/about/offices/list/osers/nidrr 202-245-7460 202-245-7316 (TTY)